Administration of Baraka Black Seed Oil for 4 weeks significantly reduced the total cholesterol level of Blood in Hyper cholesteroleamic Patients. There were significant changes in LDL cholesterol and triglycerides. Thus Baraka oil reduces the risks of coronary diseases.

Seeds of Nigella Sativa is a common drug used in Ayurvedic System of medicine in Sri Lanka. The seeds contain the Alkaloids, Essential Oils and Fixed Oils. They are aromatic stimulant with sharp taste having anthelmintic and carminative properties. They are used in lung disoredrs, cough and Jaundice both internally and externally. The seeds of Nigella Sativa are also used in the treatment of hydrophobia, Tertiary fever, Paralysis, and sour eyes. The powdered seeds mixed with gingerly oil is applied on eruption of the skin.

Hupocholesteroleamic Activity, and Hypolipemic Activity of Nigella Sativa in rats has been reported earlier. effect (general) of Nigella Sativa (powder form) has been found in rats by giving 2-8 gm/kg body weight.2 No any toxic effect of the Baraka Black Seed Oil in mouse had been found by the dose of 10 ml/kg. 3

In this study we planned to evaluate the hypocholesteroleamic activity of the Baraka Black Seed Oil in Hypercholesteroleamic patients.

Hypercholesteroleamic patients (40 y - 70 y age group) of both genders were included in the study. We selected the patients from out door clinic of Ayurvedic Teaching Hospital, Rajagiriya and Nawinna Ayurvedic Research Institute.

Figure 1 shows Serum Lipid levels in hypercholesteroleamic patient’s blood before and after the treatment.

Before the trial period total cholesterol level in patients blood as 260.8 + 43.69 mg/dl LDL cholesterol was 149.2 + 56.03 mg/dl HDL cholesterol was 89.92 + 27.86 mg/dl and serum Triglecerides was 114.59 + 25.86 mgkdl. After the trial period total cholesterol level in patient’s blood was 208.29 + 33.05 mg/dl , LDL cholesterol was 118.11 + 38.53 mg/dl , HDL cholesterol was 73.00 + 21.84 mg/dl and serum Triglecerides was 102.75 + 35.65 mg/dl.

Total cholesterol fell by 20% to (p < 0.001) 208.29 + 73.00 mg/dl , LDL cholesterol levels were reduced to 118.11 + 38.53 mg/dl , HDL cholesterol levels were reduced to 73.00 + 21.84 mg/dl after the trial period.

There is significatnt reduction in total, and LDL, HDL cholesterols and no significant change was noted in Trigleceride levels.

The mean age of patients was 52.64 + 8.8 year and this group had 9 males and 8 females.

Administration of the Baraka Black Seed Oil for 4 weeks has significantly reduced the blood level of total cholesterol and its LDL, HDL fractions in Hyper cholesteroleamic patients. There has been no significant change Triglycerides. Lowering of the total and LDL cholesterol will also reduce their ratio with HDL cholesterol. Thus reducing the risk for coronary artery disease. This could be an important step in the management of Hyper cholesteroleamic patients.

Author wish to thank Director of Institute of Indigenouse Medicine, University of Colombo, for his permission to carry out this work and EXPOLANKA COMMODITIES (PVT) LTD. for their financial support for the project.